Aneuploidy is the presence of an abnormal number of chromosomes in a cell, for example a human cell having 45 or 47 chromosomes instead of the usual 46. It does not include a difference of one or more complete sets of chromosomes.A cell with any number of complete chromosome sets is called a euploid cell.. An extra or missing chromosome is a common cause of some genetic disorders.. Constitutional aneuploidy, prevalent in conditions such as Down syndrome, typically arises through fertilization of an aneuploid gamete generated through defective chromosome segregation during meiosis. Somatic aneuploidy is acquired through defective chromosome segregation in mitosis and is characteristic of individuals with MVA and is found.

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Constitutional aneuploidy, prevalent in conditions such as Down syndrome, typically arises through fertilization of an aneuploid gamete generated through defective chromosome segregation during meiosis. Somatic aneuploidy is acquired through defective chromosome segregation in mitosis and is characteristic of individuals with MVA and is found.. Constitutional aneuploidy, prevalent in conditions such as Down syndrome, typically arises through fertilization of an aneuploid gamete generated through defective chromosome segregation during meiosis. Somatic aneuploidy is acquired through defective chromosome segregation in mitosis and is characteristic of individuals with MVA and is found.